Calm3 - calmodulin 3 Gene

Also Known as CaMA; Cam3; Camc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12315

Summary

Predicted to enable several functions, including N-terminal myristoylation domain binding activity; enzyme activator activity; and enzyme binding activity. Acts upstream of or within G2/M transition of mitotic cell cycle. Located in myelin sheath. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; familial hypertrophic cardiomyopathy; long QT syndrome 14; and long QT syndrome 15. Orthologous to human CALM1 (Calmodulin 1); CALM2 (Calmodulin 2); and CALM3 (Calmodulin 3). [provided by Alliance of Genome Resources, Apr 2022]

Calm3 Products (1)

mRNA Protein Name
NM_007590.3 NP_031616.1 calmodulin-3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within G2/M transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
2469574 MGI
involved in presynaptic endocytosis IDA
IDA: Inferred from direct assay
31628181 MGI
involved in presynaptic endocytosis IMP
IMP: Inferred from mutant phenotype
31628181 MGI
Cellular Component GO Annotation Evidence References Source
is active in calyx of Held IDA
IDA: Inferred from direct assay
31628181 MGI
is active in calyx of Held IMP
IMP: Inferred from mutant phenotype
31628181 MGI
located in myelin sheath IDA
IDA: Inferred from direct assay
19855925 MGI
part of voltage-gated potassium channel complex IGI
IGI: Inferred from genetic interaction
12223552 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calmodulin-3

  • caM

Calm3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Calm1 P0DP27 Kcnma1 Mus musculus Q08460
Anti Bait CoIP
19423573
Intra
Calm1 P0DP27 Kcnma1 Mus musculus Q08460
Confocal
19423573
Cross
Calm1 P0DP27 PPEF2 Homo sapiens O14830
Y2H
12051765
Cross
Calm1 P0DP27 PPEF2 Homo sapiens O14830
SPR
12051765
Intra
Calm1 P0DP27 Ccp110 Mus musculus Q7TSH4
Y2H
15102471
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01842 CALM3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Calm3 NCBI NCBI:808