2. Gene
  3. Casp6 - caspase 6 Gene

Casp6 - caspase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mch2; CASP-6

Gene ID: 12368 | Gene type: protein coding

About Casp6

Chromosome 3: 129,695,074-129,707,752 forward strand.GRCm39:CM000996.3

This gene has 4 transcripts (splice variants), 268 orthologues, 11 paralogues and is associated with 7 phenotypes. Ubiquitous expression in duodenum adult (RPKM 36.2), small intestine adult (RPKM 29.7) and 27 other tissues.

Summary

This gene encodes a member of the cysteine proteases that plays important roles in regulating Apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]

Casp6 Products(1)

mRNA Protein Name
NM_009811.4 NP_033941.3 caspase-6 precursor

Casp6 Protein Structure

CASc

CASc: smart00115 (19 - 271)

  • 0
  • 100
  • 200
  • 276 a.a.
Protein Preferred Names Protein Names

caspase-6

apoptotic protease Mch-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01959 CASP6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01960 Casp6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01961 CASP6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Casp6 NCBI NCBI:839