2. Gene
  3. AFMID - arylformamidase Gene

AFMID - arylformamidase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KF; FKF; KFA

Gene ID: 125061 | Gene type: protein coding

About AFMID

This gene has 15 transcripts (splice variants), 189 orthologues and 5 paralogues. Broad expression in kidney (RPKM 25.1), liver (RPKM 16.9) and 25 other tissues.

Summary

Predicted to enable hydrolase activity. Predicted to be involved in tryptophan catabolic process to kynurenine. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

AFMID Products(11)

mRNA Protein Name
NM_001010982.5 NP_001010982.2 kynurenine formamidase isoform 2
NM_001145526.3 NP_001138998.1 kynurenine formamidase isoform 1
NM_001391999.1 NP_001378928.1 kynurenine formamidase isoform 3
NM_001392000.1 NP_001378929.1 kynurenine formamidase isoform 4
NM_001392001.1 NP_001378930.1 kynurenine formamidase isoform 5
NM_001392002.1 NP_001378931.1 kynurenine formamidase isoform 6
NM_001392003.1 NP_001378932.1 kynurenine formamidase isoform 7
NM_001392004.1 NP_001378933.1 kynurenine formamidase isoform 8
NM_001392005.1 NP_001378934.1 kynurenine formamidase isoform 9
NM_001392006.1 NP_001378935.1 kynurenine formamidase isoform 10
NM_001392007.1 NP_001378936.1 kynurenine formamidase isoform 11

AFMID Protein Structure

Abhydrolase_3

Abhydrolase_3: alpha/beta hydrolase fold (92 - 279)

  • 0
  • 100
  • 200
  • 303 a.a.
Protein Preferred Names Protein Names

kynurenine formamidase

KFase

Related Diseases

Diseases Alias
Hypertryptophanemia

HYPTRP

Hypertryptophanemia, Familial

Familial Hypertryptophanemia
Glaucomatocyclitic Crisis

Posner-Schlossman Syndrome

Terrien-Viel Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00434 AFMID Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus AFMID RGD RGD:1591143
Mus musculus AFMID MGD MGI:2448704
Bos taurus AFMID VGNC VGNC:25716
Felis catus AFMID VGNC VGNC:97342
Macaca mulatta AFMID VGNC VGNC:81345