7 Results for "

125113

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "125113" in MCE Product Catalog:

Cat. No.: HY-19286
CAS No.: 202340-45-2
Synonyms: F 12511
Target:  

Acyltransferase

Research Areas:  

Cancer

Eflucimibe (F 12511) is a new acyl-coenzyme A cholesterol O-acyltransferase (ACAT) inhibitor. Eflucimibe can be used in the research of atherosclerosis .
Cat. No.: HY-W741575
CAS No.: 475110-48-6
Synonyms: P95-12113
Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone (HY-17410). Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pKi of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C .
Cat. No.: HY-R00089
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-12113 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
Cat. No.: HY-167717
CAS No.: 191791-65-8
Synonyms: (Rac)-F 12511
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(Rac)-Eflucimibe ((Rac)-F 12511) is an ACAT inhibitor with endogenous hypercholesterolemia modulating activity. (Rac)-Eflucimibe has shown high potency and efficacy as an anti-hypercholesterol compound in different hypercholesterolemia animal models .
Cat. No.: HY-R00089A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-12113 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Cat. No.: HY-RI00089
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-12113 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-RI00089A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-12113 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.