Cd68 - CD68 antigen Gene

Also Known as Lamp4; gp110; Scard1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12514

Summary

Involved in several processes, including cellular response to lipopolysaccharide; cellular response to oxidised low-density lipoprotein particle stimulus; and negative regulation of dendritic cell antigen processing and presentation. Acts upstream of or within aging and cellular response to organic substance. Located in lysosome and plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart blood vessel; liver; and spleen. Orthologous to human CD68 (CD68 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd68 Products (1)

mRNA Protein Name
NM_001291058.1 NP_001277987.1 macrosialin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
16157452 MGI
involved in cellular response to nutrient levels IDA
IDA: Inferred from direct assay
16157452 MGI
involved in cellular response to oxidised low-density lipoprotein particle stimulus IDA
IDA: Inferred from direct assay
16157452 MGI
involved in inflammatory response to antigenic stimulus IDA
IDA: Inferred from direct assay
16157452 MGI
involved in negative regulation of dendritic cell antigen processing and presentation IMP
IMP: Inferred from mutant phenotype
21572087 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
21572087 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
21572087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

macrosialin

Recombinant Cd68 Proteins

Cat. No. Product Name Accession Purity
HY-P74278 CD68 Protein, Mouse (sf9, His) P31996 (D21-S291) ≥ 90%, as determined by reducing SDS-PAGE.

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd68 NCBI NCBI:968