SLC44A3 - solute carrier family 44 member 3 Gene

Also Known as CTL3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 126969

About SLC44A3

This gene has 10 transcripts (splice variants), 154 orthologues and 4 paralogues. Broad expression in kidney (RPKM 8.6), colon (RPKM 8.5) and 20 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC44A3 Products (8)

mRNA Protein Name
NM_001114106.3 NP_001107578.1 choline transporter-like protein 3 isoform 1
NM_001258340.2 NP_001245269.1 choline transporter-like protein 3 isoform 3
NM_001258341.2 NP_001245270.1 choline transporter-like protein 3 isoform 4
NM_001258342.2 NP_001245271.1 choline transporter-like protein 3 isoform 5
NM_001258343.2 NP_001245272.1 choline transporter-like protein 3 isoform 6
NM_001301079.2 NP_001288008.1 choline transporter-like protein 3 isoform 7
NM_001350223.1 NP_001337152.1 choline transporter-like protein 3 isoform 8
NM_152369.5 NP_689582.2 choline transporter-like protein 3 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC44A3 Protein Structure

Choline_transpo

Choline_transpo: Plasma-membrane choline transporter (287 - 606)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 653 a.a.
Protein Preferred Names Protein Names

choline transporter-like protein 3

SLC44A3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC44A3 Q8N4M1 FHL3 Homo sapiens Q13643
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Cystinuria

  • CSNU

  • Cystinuria Type B

  • Cystinuria Type A

  • Cystinuria, Type I, Formerly

  • Csnu1, Formerly

  • Cystinuria, Type Ii, Formerly

  • Cystinuria, Type Iii, Formerly

  • Csnu3, Formerly

  • Cystinuria, Type Non-I, Formerly

  • Cystinuria-Lysinuria

  • Cystinuria-Lysinuria Syndrome

  • Csnu1

  • Csnu3

  • Cystinuria 1

  • Cystinuria Type A/B

  • Cystinuria Type I

  • Cystinuria Type Ii

  • Cystinuria Type Iii

  • Cystinuria Type Non-I

  • Cystinuria, Type A/B

  • Cystinuria Type 1

  • Cystinuria - Lysinuria

  • Csnu - [Cystinuria]

  • Cystine Disease
Iminoglycinuria

  • Iminoglycinuria, Digenic

  • IG
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13253 SLC44A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SLC44A3 VGNC VGNC:46419
Felis catus SLC44A3 VGNC VGNC:65373
Rattus norvegicus SLC44A3 RGD RGD:1305808
Bos taurus SLC44A3 VGNC VGNC:34877
Macaca mulatta SLC44A3 VGNC VGNC:77582
Mus musculus SLC44A3 MGD MGI:2384860
Others SLC44A3 NCBI