ARL8A - ADP ribosylation factor like GTPase 8A Gene

Homo sapiens

Also known as GIE2; ARL10B

Gene ID: 127829 | Gene type: protein coding

About ARL8A

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:202,133,404-202,144,737 (from NCBI)

This gene has 4 transcripts (splice variants), 206 orthologues and 30 paralogues. Ubiquitous expression in brain (RPKM 56.4), bone marrow (RPKM 24.8) and 25 other tissues.

Summary

Enables GTP binding activity. Predicted to be involved in chromosome segregation. Located in cytoplasm; midbody; and spindle midzone. [provided by Alliance of Genome Resources, Apr 2022]

ARL8A Products(2)

mRNA	Protein	Name
NM_001256129.2	NP_001243058.1	ADP-ribosylation factor-like protein 8A isoform 2
NM_138795.4	NP_620150.1	ADP-ribosylation factor-like protein 8A isoform 1

ARL8A Protein Structure

Arf

0
100
186 a.a.

Protein Preferred Names

Protein Names

ADP-ribosylation factor-like protein 8A

ADP-ribosylation factor-like 10B

Related Diseases

Diseases

Alias

Non-Proliferative Fibrocystic Change Of The Breast

Non-Proliferative Fibrocystic Change

Breast Fibrocystic Change, Non-Proliferative Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00998	ARL8A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ARL8A	RGD	RGD:1565940
Felis catus	ARL8A	VGNC	VGNC:59929
Macaca mulatta	ARL8A	VGNC	VGNC:69900
Bos taurus	ARL8A	VGNC	VGNC:26153
Mus musculus	ARL8A	MGD	MGI:1915974

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