DCBLD2 - discoidin, CUB and LCCL domain containing 2 Gene

Also Known as ESDN; CLCP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 131566

About DCBLD2

Cytogenetic location: 3q12.1 Genomic coordinates (GRCh38): 3:98,795,941-98,901,695 (from NCBI)

This gene has 10 transcripts (splice variants), 211 orthologues and 35 paralogues. Broad expression in testis (RPKM 18.8), heart (RPKM 11.1) and 22 other tissues.

Summary

Involved in negative regulation of cell growth and wound healing. Located in cell surface. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

DCBLD2 Products (1)

mRNA Protein Name
NM_080927.4 NP_563615.3 discoidin, CUB and LCCL domain-containing protein 2 precursor

DCBLD2 Protein Structure

CUB

CUB: CUB domain (72 - 184)

LCCL

LCCL: LCCL domain (195 - 277)

F5_F8_type_C

F5_F8_type_C: F5/8 type C domain (307 - 446)

  • 0
  • 200
  • 400
  • 600
  • 775 a.a.
Protein Preferred Names Protein Names

discoidin, CUB and LCCL domain-containing protein 2

  • 1700055P21Rik

DCBLD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DCBLD2 Q96PD2 CRKL Homo sapiens P46109
Pull Down
23770091
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant DCBLD2 Proteins

Cat. No. Product Name Accession Purity
HY-P70095 DCBLD2 Protein, Human (HEK293, His) Q96PD2-1 (Q67-A528) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03570 DCBLD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18707 Dcbld2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25194 Dcbld2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990397 Anti-DCBLD2/ESDN Antibody (FA19-1) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DCBLD2 VGNC VGNC:61362
Bos taurus DCBLD2 VGNC VGNC:27909
Canis familiaris DCBLD2 VGNC VGNC:39798
Rattus norvegicus DCBLD2 RGD RGD:620543
Macaca mulatta DCBLD2 VGNC VGNC:71704
Mus musculus DCBLD2 MGD MGI:1920629
Others DCBLD2 NCBI