PRRC1 - proline rich coiled-coil 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 133619

About PRRC1

This gene has 6 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in thyroid (RPKM 18.8), endometrium (RPKM 14.7) and 25 other tissues.

Summary

Predicted to enable identical protein binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in activation of protein kinase A activity. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PRRC1 Products (2)

mRNA Protein Name
NM_001286808.2 NP_001273737.1 protein PRRC1 isoform 1
NM_130809.5 NP_570721.1 protein PRRC1 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRRC1 Protein Structure

NTPase_I-T

NTPase_I-T: Protein of unknown function DUF84 (264 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 445 a.a.
Protein Preferred Names Protein Names

protein PRRC1

  • proline-rich and coiled-coil-containing protein 1

PRRC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRRC1 Q96M27 PIN1 Homo sapiens Q13526
Y2H Prey Pooling
25416956
Intra
PRRC1 Q96M27 SEC23B Homo sapiens Q15437
Y2H Array
25416956
Intra
PRRC1 Q96M27 SEC23B Homo sapiens Q15437
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Dystonia 23

  • DYT23

  • Adult-Onset Cervical Dystonia, Dyt23 Type

  • Dystonia, Type 23
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11235 PRRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PRRC1 VGNC VGNC:64389
Rattus norvegicus PRRC1 RGD RGD:1565632
Mus musculus PRRC1 MGD MGI:1916106
Macaca mulatta PRRC1 VGNC VGNC:76329
Canis familiaris PRRC1 VGNC VGNC:45051
Bos taurus PRRC1 VGNC VGNC:33403
Others PRRC1 NCBI