UBLCP1 - ubiquitin like domain containing CTD phosphatase 1 Gene

Also Known as CPUB1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 134510

About UBLCP1

Cytogenetic location: 5q33.3 Genomic coordinates (GRCh38): 5:159,263,290-159,286,036 (from NCBI)

This gene has 3 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in testis (RPKM 19.2), brain (RPKM 17.4) and 25 other tissues.

Summary

Enables protein serine/threonine Phosphatase activity. Involved in protein dephosphorylation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

UBLCP1 Products (1)

mRNA Protein Name
NM_145049.5 NP_659486.2 ubiquitin-like domain-containing CTD phosphatase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables proteasome regulatory particle binding IPI
IPI: Inferred from physical interaction
28539385 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
21949367 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ATP-dependent activity IDA
IDA: Inferred from direct assay
28539385 GOA
involved in regulation of proteasome assembly IMP
IMP: Inferred from mutant phenotype
28539385 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
21949367 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBLCP1 Protein Structure

ubiquitin

ubiquitin: Ubiquitin family (18 - 76)

NIF

NIF: NLI interacting factor-like phosphatase (138 - 300)

  • 0
  • 100
  • 200
  • 300
  • 318 a.a.
Protein Preferred Names Protein Names

ubiquitin-like domain-containing CTD phosphatase 1

  • CTD phosphatase-like with ubiquitin domain 1

UBLCP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UBLCP1 Q8WVY7 PSMD2 Homo sapiens Q13200
Anti Tag CoIP
27880917
Intra
UBLCP1 Q8WVY7 PSMD2 Homo sapiens Q13200
Y2H Prey Pooling
25416956
Intra
UBLCP1 Q8WVY7 PSMD2 Homo sapiens Q13200
Y2H Prey Pooling
32296183
Intra
UBLCP1 Q8WVY7 PSMD2 Homo sapiens Q13200
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15378 UBLCP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus UBLCP1 VGNC VGNC:36609
Mus musculus UBLCP1 MGD MGI:1933105
Rattus norvegicus UBLCP1 RGD RGD:1310386
Macaca mulatta UBLCP1 VGNC VGNC:79684
Canis familiaris UBLCP1 VGNC VGNC:48080
Felis catus UBLCP1 VGNC VGNC:66777