2. Gene
  3. ADAT2 - adenosine deaminase tRNA specific 2 Gene

ADAT2 - adenosine deaminase tRNA specific 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as TAD2; DEADC1; dJ20N2; dJ20N2.1

Gene ID: 134637 | Gene type: protein coding

About ADAT2

Cytogenetic location: 6q24.2 Genomic coordinates (GRCh38): 6:143,422,832-143,450,695 (from NCBI)

This gene has 3 transcripts (splice variants), 198 orthologues and 1 paralogue. Ubiquitous expression in skin (RPKM 2.8), lymph node (RPKM 2.6) and 25 other tissues.

Summary

Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ADAT2 Products(2)

mRNA Protein Name
NM_001286259.2 NP_001273188.1 tRNA-specific adenosine deaminase 2 isoform b
NM_182503.3 NP_872309.2 tRNA-specific adenosine deaminase 2 isoform a

ADAT2 Protein Structure

dCMP_cyt_deam_1

dCMP_cyt_deam_1: Cytidine and deoxycytidylate deaminase zinc-binding region (21 - 125)

  • 0
  • 100
  • 191 a.a.
Protein Preferred Names Protein Names

tRNA-specific adenosine deaminase 2

adenosine deaminase, tRNA-specific 2, TAD2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00321 ADAT2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ADAT2 VGNC VGNC:69490
Felis catus ADAT2 VGNC VGNC:59609
Bos taurus ADAT2 VGNC VGNC:25638
Rattus norvegicus ADAT2 RGD RGD:1309642
Mus musculus ADAT2 MGD MGI:1914007
Canis familiaris ADAT2 VGNC VGNC:37614