Ect2 - ect2 oncogene Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 13605
Summary
Enables small GTPase binding activity. Involved in positive regulation of neuron differentiation and positive regulation of protein import into nucleus. Acts upstream of or within cell morphogenesis. Located in cytoplasm and nucleus. Is expressed in brain ventricular layer; liver; and rest of cerebellum marginal layer. Orthologous to human ECT2 (epithelial cell transforming 2). [provided by Alliance of Genome Resources, Apr 2022]
Ect2 Products (26)
| mRNA | Protein | Name |
|---|---|---|
| NM_001177625.2 | NP_001171096.1 | protein ECT2 isoform 2 |
| NM_001177626.2 | NP_001171097.1 | protein ECT2 isoform 2 |
| NM_001409697.1 | NP_001396626.1 | protein ECT2 isoform 3 |
| NM_001409704.1 | NP_001396633.1 | protein ECT2 isoform 1 |
| NM_001409705.1 | NP_001396634.1 | protein ECT2 isoform 1 |
| NM_001409706.1 | NP_001396635.1 | protein ECT2 isoform 1 |
| NM_001409707.1 | NP_001396636.1 | protein ECT2 isoform 1 |
| NM_001409708.1 | NP_001396637.1 | protein ECT2 isoform 1 |
| NM_001409709.1 | NP_001396638.1 | protein ECT2 isoform 4 |
| NM_001409710.1 | NP_001396639.1 | protein ECT2 isoform 4 |
| NM_001409711.1 | NP_001396640.1 | protein ECT2 isoform 4 |
| NM_001409712.1 | NP_001396641.1 | protein ECT2 isoform 5 |
| NM_001409713.1 | NP_001396642.1 | protein ECT2 isoform 2 |
| NM_001409714.1 | NP_001396643.1 | protein ECT2 isoform 2 |
| NM_001409715.1 | NP_001396644.1 | protein ECT2 isoform 2 |
| NM_001409716.1 | NP_001396645.1 | protein ECT2 isoform 6 |
| NM_001409717.1 | NP_001396646.1 | protein ECT2 isoform 6 |
| NM_001409718.1 | NP_001396647.1 | protein ECT2 isoform 6 |
| NM_001409719.1 | NP_001396648.1 | protein ECT2 isoform 7 |
| NM_001409720.1 | NP_001396649.1 | protein ECT2 isoform 8 |
| NM_001409721.1 | NP_001396650.1 | protein ECT2 isoform 9 |
| NM_001409722.1 | NP_001396651.1 | protein ECT2 isoform 10 |
| NM_001409723.1 | NP_001396652.1 | protein ECT2 isoform 11 |
| NM_001409724.1 | NP_001396653.1 | protein ECT2 isoform 11 |
| NM_001409725.1 | NP_001396654.1 | protein ECT2 isoform 12 |
| NM_007900.4 | NP_031926.2 | protein ECT2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
8464478 | MGI |
| enables small GTPase binding |
IPI
IPI: Inferred from physical interaction
|
8464478 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within cell morphogenesis |
IDA
IDA: Inferred from direct assay
|
8464478 | MGI |
| involved in positive regulation of neuron differentiation |
IMP
IMP: Inferred from mutant phenotype
|
21350944 | MGI |
| involved in positive regulation of protein import into nucleus |
IDA
IDA: Inferred from direct assay
|
17904126 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
17904126 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
17904126 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein ECT2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-104023 | ZK-Thiazolidinone | Inhibitor | / | Unkown |
| HY-RS04149 | ECT2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS04150 | ECT2L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS22150 | Ect2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28671 | Ect2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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