Eya2 - EYA transcriptional coactivator and phosphatase 2 Gene

Also Known as Eab1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14049

Summary

This gene encodes a member of the eyes absent protein family. The encoded protein is a tyrosine Phosphatase which acts as a transcriptional activator during development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Eya2 Products (3)

mRNA Protein Name
NM_001271962.2 NP_001258891.1 eyes absent homolog 2
NM_001271963.2 NP_001258892.1 eyes absent homolog 2
NM_010165.4 NP_034295.1 eyes absent homolog 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20956555 MGI
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
14628052 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: Inferred from direct assay
11700312 MGI
acts upstream of or within mitochondrial outer membrane permeabilization IDA
IDA: Inferred from direct assay
11700312 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: Inferred from direct assay
14628052 MGI
acts upstream of or within striated muscle tissue development IGI
IGI: Inferred from genetic interaction
17098221 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11700312 MGI
NOT located in nucleolus IDA
IDA: Inferred from direct assay
11700312 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11700312 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eyes absent homolog 2

  • eyes absent 2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-138657 NCGC00378430 Inhibitor 98.07% Unkown
HY-133512 NCGC00249987 Inhibitor 99.58% Unkown
HY-133511 MLS000544460 Inhibitor 99.42% Unkown
HY-162592 EYA2-IN-1 / Unkown
HY-RS04612 EYA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19599 Eya2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26095 Eya2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eya2 NCBI NCBI:2139