2 Results for "

148254

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "148254" in MCE Product Catalog:

製品番号: HY-148254
CAS 番号: 2705841-52-5
純度:  99.78%
Target:  

Deubiquitinase

研究分野:  

Cancer

8RK64, a chemical probe, is a covalent UCHL1 inhibitor (IC50: 0.32 μM) . 8RK64 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
製品番号: HY-D1726
CAS 番号: 2705841-53-6
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC50 close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .