CCDC117 - coiled-coil domain containing 117 Gene

Also Known as dJ366L4.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 150275

Summary

Involved in positive regulation of DNA repair and positive regulation of cell population proliferation. Located in mitotic spindle. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in testis (RPKM 25.5), placenta (RPKM 10.2) and 24 other tissues.

CCDC117 Products (4)

mRNA Protein Name
NM_001284263.2 NP_001271192.1 coiled-coil domain-containing protein 117 isoform b
NM_001284264.2 NP_001271193.1 coiled-coil domain-containing protein 117 isoform c
NM_001284265.1 NP_001271194.1 coiled-coil domain-containing protein 117 isoform d
NM_173510.4 NP_775781.1 coiled-coil domain-containing protein 117 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19875381 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA repair IMP
IMP: Inferred from mutant phenotype
30742009 GOA
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
30742009 GOA
Cellular Component GO Annotation Evidence References Source
located in mitotic spindle IDA
IDA: Inferred from direct assay
30742009 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC117 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC117 Q8IWD4 STIP1 Homo sapiens P31948
Lumier
25036637
Intra
CCDC117 Q8IWD4 STIP1 Homo sapiens P31948
Anti Tag CoIP
33961781
Intra
CCDC117 Q8IWD4 HSP90AA1 Homo sapiens P07900
Lumier
25036637
Intra
CCDC117 Q8IWD4 HSP90AA1 Homo sapiens P07900
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02025 CCDC115 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02027 CCDC127 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02029 CCDC137 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02036 CCDC17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown