Lamp1 - lysosomal-associated membrane protein 1 Gene
Also Known as P2B; Perk; LGP-A; CD107a; Lamp-1; LGP-120
Species: Mus musculus
Summary
Enables protein domain specific binding activity. Involved in protein stabilization. Located in several cellular components, including cytoplasmic vesicle; sarcolemma; and vacuole. Is expressed in several structures, including 1-cell stage embryo; central nervous system; craniocervical region bone; extraembryonic component; and gut. Orthologous to human LAMP1 (lysosomal associated membrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Lamp1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001317353.1 | NP_001304282.1 | lysosome-associated membrane glycoprotein 1 isoform 1 precursor |
| NM_010684.3 | NP_034814.2 | lysosome-associated membrane glycoprotein 1 isoform 2 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16674683 | MGI |
| enables protein domain specific binding |
IPI
IPI: Inferred from physical interaction
|
22641697 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in protein stabilization |
IMP
IMP: Inferred from mutant phenotype
|
22641697 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in autolysosome |
IDA
IDA: Inferred from direct assay
|
26284655 | MGI |
| located in autophagosome membrane |
IDA
IDA: Inferred from direct assay
|
31006538 | MGI |
| is active in cell surface |
IDA
IDA: Inferred from direct assay
|
16760431 | MGI |
| located in cell surface |
IDA
IDA: Inferred from direct assay
|
16674683 | MGI |
| located in cytolytic granule |
IDA
IDA: Inferred from direct assay
|
19915045 | MGI |
| located in endosome |
IDA
IDA: Inferred from direct assay
|
10787428 | MGI |
| located in external side of plasma membrane |
IDA
IDA: Inferred from direct assay
|
16973387 | MGI |
| located in late endosome |
IDA
IDA: Inferred from direct assay
|
12446704 | MGI |
| is active in lysosome |
IDA
IDA: Inferred from direct assay
|
17185018 | MGI |
| located in lysosome |
IDA
IDA: Inferred from direct assay
|
10787428 | MGI |
| located in melanosome |
IDA
IDA: Inferred from direct assay
|
11266470 | MGI |
| located in multivesicular body |
IDA
IDA: Inferred from direct assay
|
11854359 | MGI |
| located in phagocytic vesicle |
IMP
IMP: Inferred from mutant phenotype
|
22190682 | MGI |
| located in phagolysosome membrane |
IDA
IDA: Inferred from direct assay
|
23395172 | MGI |
| located in sarcolemma |
IDA
IDA: Inferred from direct assay
|
14506282 | MGI |
| located in synaptic vesicle |
IDA
IDA: Inferred from direct assay
|
15073168 | MGI |
| located in vesicle |
IDA
IDA: Inferred from direct assay
|
10787428 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lysosome-associated membrane glycoprotein 1 |
|
|
Recombinant Lamp1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72526 | LAMP1/CD107a Protein, Mouse (HEK293, His) | P11438 (L25-N370) | ≥ 95%, as determined by reducing SDS-PAGE. |
Lamp1 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P89823 | LAMP1 Antibody (YA9167) | WB, ICC/IF, IF-Tissue, IP | human, mouse, rat |