Msi1 - musashi RNA-binding protein 1 Gene

Also Known as Msi1h; Musahi1; m-Msi-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17690

Summary

Enables identical protein binding activity and poly(U) RNA binding activity. Predicted to be involved in response to hormone. Located in cytoplasm and nucleus. Part of polysome. Is expressed in central nervous system; gut; ovary; sensory organ; and skin. Orthologous to human MSI1 (musashi RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Msi1 Products (5)

mRNA Protein Name
NM_001376960.1 NP_001363889.1 RNA-binding protein Musashi homolog 1 isoform 2
NM_001376961.1 NP_001363890.1 RNA-binding protein Musashi homolog 1 isoform 3
NM_001376962.1 NP_001363891.1 RNA-binding protein Musashi homolog 1 isoform 4
NM_001376963.1 NP_001363892.1 RNA-binding protein Musashi homolog 1 isoform 5
NM_008629.2 NP_032655.1 RNA-binding protein Musashi homolog 1 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
26197342 MGI
enables molecular condensate scaffold activity IDA
IDA: Inferred from direct assay
32225071 MGI
enables poly(U) RNA binding IDA
IDA: Inferred from direct assay
11588182 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
32225071 MGI
enables single-stranded RNA binding IDA
IDA: Inferred from direct assay
11588182 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11588182 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15076722 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein Musashi homolog 1

  • Musashi homolog 1(Drosophila)

  • musashi-1

Msi1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Msi1 Q61474 Msi1 Mus musculus Q61474
Pull Down
26197342
Intra
Msi1 Q61474 CPEB1 Homo sapiens Q9BZB8
Pull Down
26197342
Intra
Msi1 Q61474 Msi1 Mus musculus Q61474
Y2H
26197342
Intra
Msi1 Q61474 CPEB4 Homo sapiens Q17RY0-2
Pull Down
26197342
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-119734 Gossypolone 96.28% Unkown
HY-RS08714 MSI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22242 Msi1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28764 Msi1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msi1 NCBI NCBI:4440