Prkcd - protein kinase C, delta Gene

Also Known as Pkcd; PKC[d]; PKCdelta; D14Ertd420e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18753

About Prkcd

Chromosome 14: 30,317,311-30,348,167 reverse strand.GRCm39:CM001007.3

This gene has 13 transcripts (splice variants), 289 orthologues, 5 paralogues and is associated with 44 phenotypes. Ubiquitous expression in colon adult (RPKM 37.2), adrenal adult (RPKM 35.9) and 25 other tissues.

Summary

Enables Insulin Receptor substrate binding activity and protein kinase C activity. Involved in several processes, including negative regulation of cellular component organization; negative regulation of Insulin Receptor signaling pathway; and negative regulation of platelet aggregation. Acts upstream of or within B cell proliferation; immunoglobulin mediated immune response; and positive regulation of apoptotic signaling pathway. Located in several cellular components, including cell-cell junction; cytoplasm; and nuclear matrix. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and heart and pericardium. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3; fatty liver disease; and hypertension. Orthologous to human PRKCD (protein kinase C delta). [provided by Alliance of Genome Resources, Apr 2022]

Prkcd Products (2)

mRNA Protein Name
NM_001310682.1 NP_001297611.1 protein kinase C delta type isoform 1
NM_011103.3 NP_035233.1 protein kinase C delta type isoform 2

Prkcd Protein Structure

C1_nPKC_theta-like_rpt1

C1_nPKC_theta-like_rpt1: cd20834 (151 - 211)

C1_nPKC_theta-like_rpt2

C1_nPKC_theta-like_rpt2: cd20837 (230 - 279)

PKc_like

PKc_like: cl21453 (350 - 665)

  • 0
  • 200
  • 400
  • 600
  • 674 a.a.
Protein Preferred Names Protein Names

protein kinase C delta type

  • nPKC-delta

  • protein kinase C, delta IV

  • protein kinase C, delta V

  • protein kinase C[d]

  • tyrosine-protein kinase PRKCD

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11122 PRKCD Human Pre-designed siRNA Set A / Unkown
HY-RS11123 Prkcd Mouse Pre-designed siRNA Set A / Unkown
HY-RS11124 Prkcd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkcd NCBI NCBI:5580