Plaur - plasminogen activator, urokinase receptor Gene

Also Known as Cd87; uPAR; u-PAR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18793

Summary

Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; and positive regulation of release of cytochrome c from mitochondria. Is integral component of plasma membrane. Is expressed in several structures, including decidua; early conceptus; and spleen. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor). [provided by Alliance of Genome Resources, Apr 2022]

Plaur Products (1)

mRNA Protein Name
NM_011113.4 NP_035243.1 urokinase plasminogen activator surface receptor precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
19667118 MGI
Cellular Component GO Annotation Evidence Références Source
located in plasma membrane IDA
IDA: Inferred from direct assay
19897580 MGI
part of serine-type endopeptidase complex IPI
IPI: Inferred from physical interaction
20133942 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urokinase plasminogen activator surface receptor

  • urokinase plasminogen activator receptor

Recombinant Plaur Proteins

Cat. No. Nom du produit Accession Pureté
HY-P77275 uPAR Protein, Mouse (HEK293, His-Fc) P35456-1/NP_035243.1 (L24-T297) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77276 uPAR Protein, Mouse (HEK293, His) P35456-1/NP_035243.1 (L24-T297) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700848 uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) P35456-1 (L24-G298) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700849 uPAR Protein, Mouse (HEK293, His-Avi) P35456-1 (L24-G298) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS10648 PLAUR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17422 Plaur Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23877 Plaur Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plaur NCBI NCBI:5329