Plcb2 - phospholipase C, beta 2 Gene

Also Known as B230399N12; B230205M18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18796

Summary

Predicted to enable G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol Phospholipase C activity; and phospholipid binding activity. Acts upstream of or within sensory perception of bitter taste. Located in cytoplasm. Is expressed in several structures, including early conceptus; genitourinary system; gut; immune system; and liver. Orthologous to human PLCB2 (Phospholipase C beta 2). [provided by Alliance of Genome Resources, Apr 2022]

Plcb2 Products (2)

mRNA Protein Name
NM_001290790.1 NP_001277719.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform b
NM_177568.2 NP_808236.2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
22728827 MGI
acts upstream of or within sensory perception of bitter taste IMP
IMP: Inferred from mutant phenotype
15759003 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21606356 MGI
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
21321602 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

  • PLC-beta-2

  • phosphoinositide phospholipase C-beta-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10653 PLCB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22731 Plcb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29245 Plcb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plcb2 NCBI NCBI:5330