2. Gene
  3. SLC10A4 - solute carrier family 10 member 4 Gene

SLC10A4 - solute carrier family 10 member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as P4

Gene ID: 201780 | Gene type: protein coding

About SLC10A4

Cytogenetic location: 4p11 Genomic coordinates (GRCh38): 4:48,483,343-48,489,526 (from NCBI)

This gene has 2 transcripts (splice variants), 223 orthologues and 5 paralogues. Biased expression in adrenal (RPKM 2.6), brain (RPKM 1.4) and 8 other tissues.

Summary

Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport and regulation of neurotransmitter loading into synaptic vesicle. Predicted to act upstream of or within adult behavior and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in cholinergic synapse; dopaminergic synapse; and serotonergic synapse. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC10A4 Products(1)

mRNA Protein Name
NM_152679.4 NP_689892.1 sodium/bile acid cotransporter 4

SLC10A4 Protein Structure

SBF

SBF: Sodium Bile acid symporter family (112 - 287)

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  • 437 a.a.
Protein Preferred Names Protein Names

sodium/bile acid cotransporter 4

Na(+)/bile acid cotransporter 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12990 SLC10A4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC10A4 VGNC VGNC:34661
Mus musculus SLC10A4 MGD MGI:3606480
Rattus norvegicus SLC10A4 RGD RGD:1309536
Felis catus SLC10A4 VGNC VGNC:65183
Macaca mulatta SLC10A4 VGNC VGNC:77553
Canis familiaris SLC10A4 VGNC VGNC:51782