RANBP3L - RAN binding protein 3 like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 202151

About RANBP3L

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:36,246,913-36,301,902 (from NCBI)

This gene has 4 transcripts (splice variants), 141 orthologues and 10 paralogues. Biased expression in brain (RPKM 8.6), kidney (RPKM 8.4) and 11 other tissues.

Summary

Enables SMAD binding activity. Predicted to be involved in several processes, including mesenchymal cell differentiation involved in bone development; negative regulation of osteoblast differentiation; and positive regulation of myoblast differentiation. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RANBP3L Products (10)

mRNA Protein Name
NM_001161429.3 NP_001154901.1 ran-binding protein 3-like isoform 1
NM_001323273.2 NP_001310202.1 ran-binding protein 3-like isoform 3
NM_001323274.2 NP_001310203.1 ran-binding protein 3-like isoform 4
NM_001323275.2 NP_001310204.1 ran-binding protein 3-like isoform 5
NM_001323276.2 NP_001310205.1 ran-binding protein 3-like isoform 6
NM_001323277.2 NP_001310206.1 ran-binding protein 3-like isoform 7
NM_001323278.2 NP_001310207.1 ran-binding protein 3-like isoform 8
NM_001323279.2 NP_001310208.1 ran-binding protein 3-like isoform 9
NM_001323280.2 NP_001310209.1 ran-binding protein 3-like isoform 10
NM_145000.5 NP_659437.3 ran-binding protein 3-like isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables SMAD binding IPI
IPI: Inferred from physical interaction
25755279 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RANBP3L Protein Structure

Ran_BP1

Ran_BP1: RanBP1 domain (288 - 378)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 465 a.a.
Protein Preferred Names Protein Names

ran-binding protein 3-like

RANBP3L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
RANBP3L Q86VV4 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
RANBP3L Q86VV4 KIF24 Homo sapiens Q5T7B8-2
Y2H Prey Pooling
32296183
Intra
RANBP3L Q86VV4 KIF24 Homo sapiens Q5T7B8-2
Y2H Array
32296183
Intra
RANBP3L Q86VV4 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
RANBP3L Q86VV4 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
RANBP3L Q86VV4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
RANBP3L Q86VV4 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
RANBP3L Q86VV4 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
RANBP3L Q86VV4 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
RANBP3L Q86VV4 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra
RANBP3L Q86VV4 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11647 RANBP3L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RANBP3L MGD MGI:2444654
Felis catus RANBP3L VGNC VGNC:64489
Macaca mulatta RANBP3L VGNC VGNC:110438
Rattus norvegicus RANBP3L RGD RGD:1307559
Bos taurus RANBP3L VGNC VGNC:33711
Others RANBP3L NCBI