Sell - selectin, lymphocyte Gene

Also Known as Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; L-selectin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20343

Summary

Enables cell adhesion molecule binding activity. Acts upstream of or within response to ATP. Located in external side of plasma membrane. Is expressed in brain; brainstem; submandibular gland epithelium; and testis. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in Crohn's disease; IgA glomerulonephritis; and ulcerative colitis. Orthologous to human SELL (Selectin L). [provided by Alliance of Genome Resources, Apr 2022]

Sell Products (4)

mRNA Protein Name
NM_001164059.1 NP_001157531.1 L-selectin isoform 2 precursor
NM_011346.2 NP_035476.1 L-selectin isoform 1 precursor
NM_001164059.1 NP_001157531.1 L-selectin isoform 2 precursor
NM_011346.2 NP_035476.1 L-selectin isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cell adhesion molecule binding IPI
IPI: Inferred from physical interaction
14597732 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11389866 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to ATP IDA
IDA: Inferred from direct assay
15914561 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
23620790 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
7589135 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11389866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

L-selectin

  • CD62 antigen-like family member L

  • LAM-1

  • LECAM1

  • leukocyte adhesion molecule 1

  • leukocyte-endothelial cell adhesion molecule 1

  • lymph node homing receptor

  • lymphocyte antigen 22

  • lymphocyte surface MEL-14 antigen

Recombinant Sell Proteins

Cat. No. Product Name Accession Purity
HY-P70312 L-selectin/CD62L Protein, Mouse (HEK293, hFc-His) P18337 (W39-N332) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P74766 L-selectin/CD62L Protein, Mouse (HEK293, His) NP_035476.1 (W39-N332) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12646 SELL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W036160 N-Fmoc-O-ethyl-L-homoserine / Unkown
HY-RS17751 Sell Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24218 Sell Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sell NCBI NCBI:6402