2. Gene
  3. Sstr2 - somatostatin receptor 2 Gene

Sstr2 - somatostatin receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SS2R; sst2; SRIF-1; SSTR-2; Smstr2; Smstr-2

Gene ID: 20606 | Gene type: protein coding

About Sstr2

Chromosome 11: 113,510,168-113,516,854 forward strand.GRCm39:CM001004.3

This gene has 3 transcripts (splice variants), 264 orthologues, 15 paralogues and is associated with 32 phenotypes. Biased expression in whole brain E14.5 (RPKM 13.8), CNS E14 (RPKM 13.2) and 13 other tissues.

Summary

The protein encoded by this gene is a receptor for somatostatin, which acts at many sites to inhibit the release of several Hormones and other secretory proteins. The encoded protein is a member of the superfamily of receptors having seven transmembrane segments and is involved in many processes, including adenylyl cyclase inhibition, phosphotyrosine Phosphatase stimulation, and inhibition of calcium entry and cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Sstr2 Products(2)

mRNA Protein Name
NM_009217.5 NP_033243.2 somatostatin receptor type 2 isoform B
NM_001042606.3 NP_001036071.1 somatostatin receptor type 2 isoform A

Sstr2 Protein Structure

7tmA_SSTR2

7tmA_SSTR2: cd15971 (43 - 322)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (44 - 70)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (77 - 103)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (114 - 144)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (156 - 178)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (204 - 233)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (248 - 278)

7tmA_SSTR2

7tmA_SSTR2: cd15971 (290 - 315)

  • 0
  • 100
  • 200
  • 300
  • 369 a.a.
Protein Preferred Names Protein Names

somatostatin receptor type 2

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0036 Octreotide Agonist 99.64% Unkown
HY-P0036B Octreotide pamoate Agonist / Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P3294 Onzigolide Agonist / Phase 2
Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1202A CYN 154806 TFA Antagonist 99.81% Unkown
HY-P4452 PRL 2915 Antagonist 99.57% Unkown
HY-P3618 Cortistatin 29 99.22% Unkown
HY-P3124A BIM-23190 hydrochloride Agonist 99.64% Unkown
HY-P0024A Veldoreotide TFA Agonist 98.37% Unkown
HY-P5362A NODAGA-LM3 TFA Antagonist / Unkown
HY-P4469 PRL 3195 Antagonist / Unkown
HY-P2545 [Tyr1]-Somatostatin-14 / Unkown
HY-P10137 Satoreotide Antagonist / Unkown
HY-P2434 AP102 / Unkown
HY-110161 sst2 Receptor agonist-1 Agonist / Unkown
HY-P3124 BIM-23190 Agonist / Unkown
HY-P5362 NODAGA-LM3 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sstr2 NCBI NCBI:6752