FERD3L - Fer3 like bHLH transcription factor Gene

Also Known as PTFB; NATO3; NTWIST; N-TWIST; bHLHa31

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 222894

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in developmental process; negative regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell development; floor plate development; and regulation of neurogenesis. Predicted to be located in chromatin and nucleus. [provided by Alliance of Genome Resources, Jun 2026]

FERD3L Products (1)

mRNA Protein Name
NM_152898.2 NP_690862.1 fer3-like protein

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FERD3L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
FERD3L Q96RJ6 FAM9B Homo sapiens Q8IZU0
Y2H Array
31515488
Intra
FERD3L Q96RJ6 FAM9B Homo sapiens Q8IZU0
Validated Y2H
25416956
Intra
FERD3L Q96RJ6 SGTA Homo sapiens O43765
Y2H Array
25416956
Intra
FERD3L Q96RJ6 SGTA Homo sapiens O43765
Validated Y2H
25416956
Intra
FERD3L Q96RJ6 TCF4 Homo sapiens P15884
Anti Tag CoIP
33961781
Intra
FERD3L Q96RJ6 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra
FERD3L Q96RJ6 TCF4 Homo sapiens P15884
Anti Tag CoIP
28514442
Intra
FERD3L Q96RJ6 MAGEB4 Homo sapiens O15481
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction