2. Gene
  3. KHNYN - KH and NYN domain containing Gene

KHNYN - KH and NYN domain containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as KIAA0323

Gene ID: 23351 | Gene type: protein coding

About KHNYN

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,423,165-24,441,843 (from NCBI)

This gene has 6 transcripts (splice variants), 100 orthologues and 6 paralogues. Ubiquitous expression in stomach (RPKM 18.8), small intestine (RPKM 18.4) and 25 other tissues.

Summary

The protein encoded by this gene contains a ribonuclease NYN domain and belongs to the N4BP1 family. The protein is a cofactor for the zinc finger Antiviral protein (ZAP protein) which targets viral RNA for degradation and restricts SARS-CoV-2 Infection. [provided by RefSeq, Sep 2021]

KHNYN Products(3)

mRNA Protein Name
NM_001290256.2 NP_001277185.1 protein KHNYN isoform 2
NM_001290257.2 NP_001277186.1 protein KHNYN isoform 1
NM_015299.3 NP_056114.1 protein KHNYN isoform 1

KHNYN Protein Structure

RNase_Zc3h12a

RNase_Zc3h12a: Zc3h12a-like Ribonuclease NYN domain (437 - 588)

  • 0
  • 200
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  • 600
  • 678 a.a.
Protein Preferred Names Protein Names

protein KHNYN

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07241 KHNYN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus KHNYN VGNC VGNC:30544
Rattus norvegicus KHNYN RGD RGD:1565688
Felis catus KHNYN VGNC VGNC:63080
Canis familiaris KHNYN VGNC VGNC:42339
Mus musculus KHNYN MGD MGI:2451333
Macaca mulatta KHNYN VGNC VGNC:73866