2. Gene
  3. SEC61G - SEC61 translocon subunit gamma Gene

SEC61G - SEC61 translocon subunit gamma Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SSS1

Gene ID: 23480 | Gene type: protein coding

About SEC61G

Cytogenetic location: 7p11.2 Genomic coordinates (GRCh38): 7:54,752,253-54,759,211 (from NCBI)

This gene has 7 transcripts (splice variants) and 250 orthologues. Ubiquitous expression in colon (RPKM 71.5), prostate (RPKM 56.4) and 25 other tissues.

Summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

SEC61G Products(2)

mRNA Protein Name
NM_001012456.2 NP_001012474.1 protein transport protein Sec61 subunit gamma
NM_014302.4 NP_055117.1 protein transport protein Sec61 subunit gamma

SEC61G Protein Structure

SecE

SecE: SecE/Sec61-gamma subunits of protein translocation complex (12 - 66)

  • 0
  • 68 a.a.
Protein Preferred Names Protein Names

protein transport protein Sec61 subunit gamma

SEC61 translocon gamma subunit

Related Diseases

Diseases Alias
Childhood Ependymoma
Autosomal Dominant Severe Congenital Neutropenia

Severe Congenital Neutropenia Autosomal Dominant

Neutropenia, Congenital, Severe, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12623 SEC61G Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SEC61G VGNC VGNC:49154
Mus musculus SEC61G MGD MGI:1202066
Rattus norvegicus SEC61G RGD RGD:1596170
Macaca mulatta SEC61G VGNC VGNC:108436
Canis familiaris SEC61G VGNC VGNC:49617