2. Gene
  3. Mapk7 - mitogen-activated protein kinase 7 Gene

Mapk7 - mitogen-activated protein kinase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BMK1; ERK5; BMK-1; ERK-5; PRKM7; Erk5-T; b2b2346Clo

Gene ID: 23939 | Gene type: protein coding

About Mapk7

Chromosome 11: 61,379,638-61,385,232 reverse strand.GRCm39:CM001004.3

This gene has 14 transcripts (splice variants), 193 orthologues, 19 paralogues and is associated with 50 phenotypes. Ubiquitous expression in limb E14.5 (RPKM 31.7), whole brain E14.5 (RPKM 29.9) and 27 other tissues.

Summary

Enables protein serine/threonine kinase activity. Involved in protein phosphorylation. Acts upstream of or within several processes, including negative regulation of intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of angiogenesis. Located in cytosol and nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; ganglia; genitourinary system; and salivary gland. Orthologous to human MAPK7 (mitogen-activated protein kinase 7). [provided by Alliance of Genome Resources, Apr 2022]

Mapk7 Products(7)

mRNA Protein Name
NM_011841.2 NP_035971.1 mitogen-activated protein kinase 7 isoform a
NM_001361989.1 NP_001348918.1 mitogen-activated protein kinase 7 isoform c
NM_001291036.1 NP_001277965.1 mitogen-activated protein kinase 7 isoform c
NM_001291034.1 NP_001277963.1 mitogen-activated protein kinase 7 isoform a
NM_001291035.1 NP_001277964.1 mitogen-activated protein kinase 7 isoform c
NM_001291037.1 NP_001277966.1 mitogen-activated protein kinase 7 isoform d
NM_001291033.1 NP_001277962.1 mitogen-activated protein kinase 7 isoform b

Mapk7 Protein Structure

STKc_ERK5

STKc_ERK5: cd07855 (48 - 383)

  • 0
  • 200
  • 400
  • 600
  • 806 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase 7

MAPK 7

big MAP kinase 1

extracellular signal-regulated kinase 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148061 DB1113 99.28% Unkown
HY-148065 FMF-06-098-1 / Unkown
HY-149412 MHJ-627 Inhibitor / Unkown
HY-RS08118 MAPK7 Human Pre-designed siRNA Set A / Unkown
HY-RS08119 Mapk7 Mouse Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk7 NCBI NCBI:5598