Pcbp1 - poly(rC) binding protein 1 Gene

Also Known as WBP17; [a]CP-1; hnRNP E1; hnRNP-E1; alphaCP-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23983

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific single stranded DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in embryo. Orthologous to human PCBP1 (poly(rC) binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pcbp1 Products (1)

mRNA Protein Name
NM_011865.4 NP_035995.1 poly(rC)-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
15836633 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
enables sequence-specific single stranded DNA binding IDA
IDA: Inferred from direct assay
15836633 MGI
enables single-stranded DNA binding IDA
IDA: Inferred from direct assay
15836633 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15836633 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16979592 MGI
is active in cytosol IMP
IMP: Inferred from mutant phenotype
8697449 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15836633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

poly(rC)-binding protein 1

  • alpha-CP1

  • heterogeneous nuclear ribonucleoprotein E1

Pcbp1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Pcbp1 P60335 Hdac9 Mus musculus Q99N13
Y2H
15102471
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10115 PCBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18184 Pcbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24658 Pcbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcbp1 NCBI NCBI:5093