Ctrb1 - chymotrypsinogen B1 Gene

Also Known as Ctrb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24291

Summary

Enables serine-type endopeptidase activity. Involved in several processes, including response to food; response to nutrient; and response to peptide hormone. Located in lysosome. Biomarker of pancreatitis. Orthologous to several human genes including CTRB2 (chymotrypsinogen B2). [provided by Alliance of Genome Resources, Apr 2022]

Ctrb1 Products (1)

mRNA Protein Name
NM_012536.2 NP_036668.2 chymotrypsinogen B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8200353 RGD
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
8635580 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
18211899 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
11733020 RGD
involved in response to cytokine IDA
IDA: Inferred from direct assay
18211899 RGD
involved in response to food IEP
IEP: Inferred from expression pattern
1709673 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
3885943 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
2468294 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
2452633 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chymotrypsinogen B

  • Chymotrypsin B

  • chymotrypsin B1

Recombinant Ctrb1 Proteins

Cat. No. Product Name Accession Purity
HY-P76852 CTRB1 Protein, Rat (HEK293, His) P07338 (C19-N263) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03317 CTRB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20006 Ctrb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26509 Ctrb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctrb1 NCBI NCBI:1504