CDC26 - cell division cycle 26 Gene

Homo sapiens

Also known as APC12; ANAPC12; C9orf17

Gene ID: 246184 | Gene type: protein coding

About CDC26

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:113,266,992-113,275,572 (from NCBI)

This gene has 2 transcripts (splice variants) and 176 orthologues. Ubiquitous expression in kidney (RPKM 9.9), appendix (RPKM 9.9) and 25 other tissues.

Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008]

CDC26 Products(1)

mRNA	Protein	Name
NM_139286.4	NP_644815.1	anaphase-promoting complex subunit CDC26

CDC26 Protein Structure

ANAPC_CDC26

0
85 a.a.

Protein Preferred Names

Protein Names

anaphase-promoting complex subunit CDC26

CDC26 subunit of anaphase promoting complex

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 27

RP27	Retinal Degeneration, Autosomal Recessive, Clumped Pigment Type
Retinal Degeneration Autosomal Recessive Clumped Pigment Type	RDCP
Clumped Pigmentary Retinal Degeneration	Retinitis Pigmentosa, Type 27

Cornea Cancer

Malignant Neoplasm Of Cornea	Neoplasm Of Cornea
Corneal Tumor	Malignant Corneal Tumor
Malignant Tumor Of Cornea	Primary Malignant Neoplasm Of Cornea

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02294	CDC26 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CDC26	VGNC	VGNC:38992
Bos taurus	CDC26	VGNC	VGNC:27065
Felis catus	CDC26	VGNC	VGNC:60652
Mus musculus	CDC26	MGD	MGI:1913690
Macaca mulatta	CDC26	VGNC	VGNC:70817
Rattus norvegicus	CDC26	RGD	RGD:1311342

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