2. Gene
  3. Prkcg - protein kinase C, gamma Gene

Prkcg - protein kinase C, gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PKC; PKCI; Prkc; Prkcc; RATPKCI

Gene ID: 24681 | Gene type: protein coding

About Prkcg

Primary_assembly 1: 65,832,855-65,859,384 reverse strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 201 orthologues, 9 paralogues and is associated with 15 phenotypes. Biased expression in Brain (RPKM 143.9), Spleen (RPKM 12.) and 2 other tissues.

Summary

Enables calcium-dependent protein kinase C activity. Involved in several processes, including long-term synaptic potentiation; protein autophosphorylation; and response to psychosocial stress. Located in several cellular components, including dendrite; perinuclear region of cytoplasm; and synaptic membrane. Is active in postsynaptic cytosol. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 14. Orthologous to human PRKCG (protein kinase C gamma). [provided by Alliance of Genome Resources, Apr 2022]

Prkcg Products(1)

mRNA Protein Name
NM_012628.2 NP_036760.1 protein kinase C gamma type

Prkcg Protein Structure

C1_cPKC_rpt1

C1_cPKC_rpt1: cd20833 (33 - 90)

C1_cPKC_rpt2

C1_cPKC_rpt2: cd20836 (100 - 153)

C2_PKC_alpha_gamma

C2_PKC_alpha_gamma: cd04026 (157 - 288)

STKc_cPKC

STKc_cPKC: cd05587 (353 - 676)

  • 0
  • 200
  • 400
  • 600
  • 697 a.a.
Protein Preferred Names Protein Names

protein kinase C gamma type

PKC-gamma

protein kinase C type I (gamma type)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11128 PRKCG Human Pre-designed siRNA Set A / Unkown
HY-RS11129 Prkcg Mouse Pre-designed siRNA Set A / Unkown
HY-RS11130 Prkcg Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkcg NCBI NCBI:5582