1. Gene
  2. EML3 - EMAP like 3 Gene

EML3 - EMAP like 3 Gene

Homo sapiens

Also known as ELP95; EMAP3; EMAP95

Gene ID: 256364 | Gene type: protein coding

About EML3

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,602,218-62,612,775 (from NCBI)

This gene has 18 transcripts (splice variants), 194 orthologues and 9 paralogues. Ubiquitous expression in spleen (RPKM 13.3), fat (RPKM 13.0) and 25 other tissues.

Summary

Predicted to enable microtubule binding activity. Involved in mitotic metaphase plate congression and regulation of mitotic spindle assembly. Located in several cellular components, including midbody; mitotic spindle microtubule; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

EML3 Products(4)

mRNA Protein Name
NM_001300793.2 NP_001287722.1 echinoderm microtubule-associated protein-like 3 isoform 1
NM_001300794.2 NP_001287723.1 echinoderm microtubule-associated protein-like 3 isoform 2
NM_001411016.1 NP_001397945.1 echinoderm microtubule-associated protein-like 3 isoform 4
NM_153265.3 NP_694997.2 echinoderm microtubule-associated protein-like 3 isoform 3

EML3 Protein Structure

HELP

HELP: HELP motif (215 - 284)

WD40

WD40: WD domain, G-beta repeat (299 - 323)

WD40

WD40: WD domain, G-beta repeat (592 - 625)

WD40

WD40: WD domain, G-beta repeat (684 - 708)

WD40

WD40: WD domain, G-beta repeat (724 - 754)

WD40

WD40: WD domain, G-beta repeat (833 - 867)

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  • 896 a.a.
Protein Preferred Names Protein Names

echinoderm microtubule-associated protein-like 3

EMAP-3

Orthologs Information

Species Symbol Source ID
Macaca mulatta EML3 VGNC VGNC:72120
Bos taurus EML3 VGNC VGNC:28477
Mus musculus EML3 MGD MGI:2387612
Felis catus EML3 VGNC VGNC:61850
Canis familiaris EML3 VGNC VGNC:40348
Rattus norvegicus EML3 RGD RGD:7630023