EEF1AKMT3 - EEF1A lysine methyltransferase 3 Gene

Also Known as FAM119B; METTL21B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25895

Summary

Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in centrosome and cytoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in thyroid (RPKM 5.3), ovary (RPKM 4.3) and 25 other tissues.

EEF1AKMT3 Products (2)

mRNA Protein Name
NM_015433.3 NP_056248.2 EEF1A lysine methyltransferase 3 isoform a
NM_206914.2 NP_996797.1 EEF1A lysine methyltransferase 3 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
23349634 GOA
enables methyltransferase activity IDA
IDA: Inferred from direct assay
28108655 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
23349634 GOA
enables protein-lysine N-methyltransferase activity IDA
IDA: Inferred from direct assay
28108655 GOA
enables protein-lysine N-methyltransferase activity IMP
IMP: Inferred from mutant phenotype
28663172 GOA
Biological Process GO Annotation Evidence References Source
involved in peptidyl-lysine methylation IDA
IDA: Inferred from direct assay
28108655 GOA
involved in peptidyl-lysine methylation IMP
IMP: Inferred from mutant phenotype
28663172 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
28108655 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
23349634 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
23349634 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EEF1AKMT3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EEF1AKMT3 Q96AZ1 ALS2CL Homo sapiens Q60I27
Y2H Prey Pooling
32296183
Intra
EEF1AKMT3 Q96AZ1 ALS2CL Homo sapiens Q60I27
Y2H Array
32296183
Intra
EEF1AKMT3 Q96AZ1 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra
EEF1AKMT3 Q96AZ1 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction