FAM162A - family with sequence similarity 162 member A Gene

Also Known as E2IG5; HGTD-P; C3orf28

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26355

About FAM162A

Cytogenetic location: 3q21.1 Genomic coordinates (GRCh38): 3:122,384,182-122,412,334 (from NCBI)

This gene has 14 transcripts (splice variants), 131 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 86.7), esophagus (RPKM 60.9) and 25 other tissues.

Summary

Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to hypoxia; and positive regulation of release of cytochrome c from mitochondria. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

FAM162A Products (1)

mRNA Protein Name
NM_014367.4 NP_055182.3 protein FAM162A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15082785 GOA
Biological Process GO Annotation Evidence References Source
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
15082785 GOA
involved in cellular response to hypoxia IDA
IDA: Inferred from direct assay
15082785 GOA
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
15082785 GOA
involved in positive regulation of release of cytochrome c from mitochondria IDA
IDA: Inferred from direct assay
15082785 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM162A Protein Structure

DUF1075

DUF1075: Protein of unknown function (DUF1075) (10 - 153)

  • 0
  • 100
  • 154 a.a.
Protein Preferred Names Protein Names

protein FAM162A

  • E2-induced gene 5 protein

FAM162A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FAM162A Q96A26 HSP90AB1 Homo sapiens P08238
Imaging
16698020
Intra
FAM162A Q96A26 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
16698020
Intra
FAM162A Q96A26 VDAC2 Homo sapiens P45880
Anti Tag CoIP
15082785
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04689 FAM162A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22003 Fam162a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28520 Fam162a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FAM162A MGD MGI:1917436
Macaca mulatta FAM162A VGNC VGNC:72291
Canis familiaris FAM162A VGNC VGNC:40612
Rattus norvegicus FAM162A RGD RGD:1590883
Felis catus FAM162A VGNC VGNC:102695
Bos taurus FAM162A VGNC VGNC:28744
Others FAM162A NCBI