5 Results for "

266553

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "266553" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P9928
CAS No.: 1245916-14-6
Synonyms: REGN 727; SAR 236553
Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation .
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1
1 Cited Publications
Cat. No.: HY-P9928A
CAS No.: 1245916-14-6
Synonyms: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and inflammation .
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Cat. No.: HY-132225
CAS No.: 158942-04-2
Purity:  99.35%
Target:  

5-HT Receptor

Research Areas:  

Inflammation/Immunology

SB 206553 is a 5-HT2C inverse agonist. SB 206553 can attenuate methamphetamine-seeking in rats. SB 206553 has activity for 5-HT2 receptor ligands in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B) and 7.8 nM (5-HT2C), respectively. SB 206553 can be used for the research of psychostimulant abuse disorders .
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Cat. No.: HY-103135
CAS No.: 1197334-04-5
Purity:  99.36%
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

SB 206553 hydrochloride is a high affinity, selective and orally active 5-HT2B / 5-HT2C receptor antagonist (rat 5-HT2B pA2 = 8.89, human 5-HT2C pKi = 7.92) . SB 206553 possesses anxiolytic-like properties .
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Cat. No.: HY-118920
CAS No.: 82337-14-2
Research Areas:  

Cardiovascular Disease

SQ 26655 is a TxA2 receptor agonist. SQ 26655 induces human platelet aggregation .
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