UTP20 - UTP20 small subunit processome component Gene

Also Known as DRIM; 1A6/DRIM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27340

About UTP20

Cytogenetic location: 12q23.2 Genomic coordinates (GRCh38): 12:101,280,105-101,386,618 (from NCBI)

This gene has 4 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in testis (RPKM 4.3), ovary (RPKM 3.4) and 25 other tissues.

Summary

UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009]

UTP20 Products (1)

mRNA Protein Name
NM_014503.3 NP_055318.2 small subunit processome component 20 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16053918 GOA
Biological Process GO Annotation Evidence References Source
involved in rRNA processing IMP
IMP: Inferred from mutant phenotype
17498821 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleolus IDA
IDA: Inferred from direct assay
16458307 GOA
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UTP20 Protein Structure

DRIM

DRIM: Down-regulated in metastasis (920 - 1063)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2785 a.a.
Protein Preferred Names Protein Names

small subunit processome component 20 homolog

  • NNP73

UTP20 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UTP20 O75691 PPP1R26 Homo sapiens Q5T8A7
Y2H
16053918
Intra
UTP20 O75691 PPP1R26 Homo sapiens Q5T8A7
Anti Tag CoIP
16053918
Intra
UTP20 O75691 PPP1R26 Homo sapiens Q5T8A7
Pull Down
16053918
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Root Caries

  • Cementum Caries

  • Dental Caries Of Root Surface
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15577 UTP20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus UTP20 VGNC VGNC:66904
Bos taurus UTP20 VGNC VGNC:36744
Mus musculus UTP20 MGD MGI:1917933
Macaca mulatta UTP20 VGNC VGNC:79100
Rattus norvegicus UTP20 RGD RGD:1560606
Canis familiaris UTP20 VGNC VGNC:48211
Others UTP20 NCBI