Rtcb - RNA 2',3'-cyclic phosphate and 5'-OH ligase Gene

Also Known as FAAP; HSPC117; D10Wsu52e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 28088

Summary

Predicted to enable RNA Ligase (ATP) activity and vinculin binding activity. Acts upstream of or within in utero embryonic development and placenta development. Located in endoplasmic reticulum membrane and nuclear envelope. Is expressed in several structures, including early conceptus and placenta. Orthologous to human RTCB (RNA 2',3'-cyclic phosphate and 5'-OH Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Rtcb Products (1)

mRNA Protein Name
NM_145422.4 NP_663397.1 RNA-splicing ligase RtcB homolog

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
20510672 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
20510672 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20510672 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
25087875 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
25087875 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-splicing ligase RtcB homolog

  • 3'-phosphate/5'-hydroxy nucleic acid ligase

  • focal adhesion-associated protein

  • tRNA-splicing ligase RtcB homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145675A (R)-TCB2 / Unkown
HY-RS12316 RTCB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20814 Rtcb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27328 Rtcb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rtcb NCBI NCBI:51493