2. Gene
  3. IL17A - interleukin 17A Gene

IL17A - interleukin 17A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus

Also known as IL17; IL-17

Gene ID: 282863 | Gene type: protein coding

About IL17A

Primary_assembly 23: 24,605,962-24,609,483 forward strand.ARS-UCD1.2:CM008190.2

This gene has 1 transcript (splice variant), 97 orthologues and 4 paralogues.

IL17A Products(1)

mRNA Protein Name
NM_001008412.2 NP_001008412.1 interleukin-17A precursor

IL17A Protein Structure

IL17

IL17: pfam06083 (66 - 144)

  • 0
  • 100
  • 153 a.a.
Protein Preferred Names Protein Names

interleukin-17A

IL-17A

interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Related Agents

Approval
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99280 Bimekizumab Antagonist 99.52% Unkown
HY-P9927 Secukinumab Inhibitor ≥99.20% Unkown
HY-P9924 Ixekizumab Inhibitor 99.00% Unkown
Clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-103637A Vimirogant hydrochloride Inhibitor 98.39% Phase 2
HY-103637 Vimirogant Inhibitor / Phase 2
HY-107390 AX-024 Inhibitor 99.73% Phase 1
HY-107390A AX-024 hydrochloride Inhibitor 99.23% Phase 1
Inhibitory Antibodies (10)
Cat. No. Product Name Effect
Purity Phase
HY-P99335 Vunakizumab Inhibitor 95.00% Phase 4
HY-P99563 Tibulizumab Inhibitor 98.86% Phase 3
HY-P99652 Gumokimab Inhibitor 98.95% Phase 3
HY-P99754 Netakimab Inhibitor 95.00% Phase 3
HY-P99515 Xeligekimab Inhibitor 95.00% Phase 3
HY-P990741 Galvokimig 97.896% Phase 2
HY-P991261 CJM-112 Inhibitor 99.65% Phase 2
HY-P991091 COVA322 Inhibitor / Phase 2
HY-P991260 CNTO-6785 Inhibitor / Phase 2
HY-P991263 SCH-900117 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (59)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15826 SGC-CBP30 Inhibitor 99.83% Unkown
HY-139206 LY3509754 Inhibitor 99.35% Unkown
HY-101913 IL-17A antagonist 1 Antagonist 99.74% Unkown
HY-P1924 IRBP(651-670) human, mouse Activator 99.64% Unkown
HY-141692 IL-17 modulator 4 Modulator 98.19% Unkown
HY-177129 Simepdekinra Antagonist 99.05% Unkown
HY-P3450 Erepdekinra Antagonist 98.63% Unkown
HY-155830 Morcamilast Inhibitor 98.92% Unkown
HY-153780 Navepdekinra Inhibitor 98.58% Unkown
HY-101915 IL-17A antagonist 3 Antagonist 99.25% Unkown
HY-119464 MRL-871 Agonist 99.11% Unkown
HY-139780 JNJ-61803534 Inhibitor 99.84% Unkown
HY-145429 IL-17A modulator-2 Modulator 98.44% Unkown
HY-N3029 Noreugenin Inhibitor 99.42% Unkown
HY-141692B (R)-IL-17 modulator 4 99.56% Unkown
HY-145430 IL-17A modulator-1 Modulator 98.80% Unkown
HY-139686 IL-17A inhibitor 2 Inhibitor 99.86% Unkown
HY-147128 PY109 Agonist 99.15% Unkown
HY-164826 Acetyl zingerone 99.34% Unkown
HY-133552 RORγt Inverse agonist 10 Antagonist 99.13% Unkown
HY-183326 Isosorbide di-(methyl fumarate) Activator 99.87% Unkown
HY-N11768 4-Methoxylonchocarpin Inhibitor 98.0% Unkown
HY-W145695 Chitoheptaose ≥98.0% Unkown
HY-155244 12R-LOX-IN-2 Inhibitor 99.85% Unkown
HY-128353 ROR agonist-1 Antagonist / Unkown
HY-141692A IL-17 modulator 4 sulfate Modulator / Unkown
HY-126252 A-9758 Inhibitor / Unkown
HY-130243 RORγt Inverse agonist 6 Antagonist 98.97% Unkown
HY-133128 FM26 Antagonist / Unkown
HY-142939 RORγt modulator 4 Modulator / Unkown
HY-148272 IL-17A modulator-3 Modulator 99.37% Unkown
HY-153276 Androgen receptor-IN-5 Inhibitor / Unkown
HY-155243 12R-LOX-IN-1 Inhibitor / Unkown
HY-158159 IL17A-IN-1 Inhibitor / Unkown
HY-162490 TF-S14 Inhibitor / Unkown
HY-168084 IL-17-IN-1 Inhibitor / Unkown
HY-168971 Paeoniflorin-6′-O-benzene sulfonate / Unkown
HY-169007 STAT3-IN-34 Inhibitor / Unkown
HY-169306 IL-17A inhibitor 4 Inhibitor / Unkown
HY-170611 IL-17-IN-3 Inhibitor / Unkown
HY-172806 PARP14 inhibitor 1 Inhibitor / Unkown
HY-178714 JNJ627 Inhibitor / Unkown
HY-179113 IL-17A-IN-5 Inhibitor / Unkown
HY-180608 TCR-IN-1 Inhibitor / Unkown
HY-181826 IL-17-IN-6 Inhibitor / Unkown
HY-181827 IL-17-IN-7 Inhibitor / Unkown
HY-182795 Colchicine derivative-1 / Unkown
HY-183370 JAK2/STAT3-IN-2 Inhibitor / Unkown
HY-183548 XW-17 Ligand / Unkown
HY-N13251 Verbena Extract / Unkown
HY-N8529 Eupalestin Inhibitor / Unkown
HY-P1924A IRBP(651-670) human, mouse TFA Activator / Unkown
HY-RS06695 IL17A Human Pre-designed siRNA Set A / Unkown
HY-RS06696 Il17a Mouse Pre-designed siRNA Set A / Unkown
HY-RS06697 Il17a Rat Pre-designed siRNA Set A / Unkown
HY-RS06701 IL17F Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174633 Human IL17A mRNA / Unkown
HY-N0976 1,11b-Dihydro-11b-hydroxymedicarpin Activator / Unkown
HY-N12481 Cephalandole B / Unkown
Inhibitory Antibodies (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990222 Anti-Mouse/Rat IL-17A Antibody (17F3) Inhibitor 99.41% Unkown
HY-P9927A Secukinumab (Anti-Human IL-17A) Antagonist 98.31% Unkown
HY-P99424 Afasevikumab Inhibitor 95% Unkown
HY-P991797 Anti-Mouse IL-17A Antibody (BZN035) Inhibitor 97.90% Unkown
HY-P991146 Lecankitug Ligand 98% Unkown
HY-P991035 Turenkibart Inhibitor / Unkown
HY-P99310 Perakizumab Inhibitor 99.79% Unkown
HY-P990761 Roconkibart 95.15% Unkown
HY-P990973 Betinukibart Inhibitor / Unkown
HY-P991116 Amdokitug 95.696% Unkown
HY-P991129 Crusekitug Ligand 97.949% Unkown
HY-P991595 HB-0017 Inhibitor / Unkown
HY-P991725 Velvakiment Inhibitor / Unkown
HY-P992045 HZD37-5 Inhibitor / Unkown
HY-P992101 Aritinercept Inhibitor / Unkown
HY-P990252 Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IL17A NCBI NCBI:3605
Canis familiaris IL17A NCBI NCBI:481837
Macaca fascicularis IL17A NCBI NCBI:102119976
Mus musculus IL17A NCBI NCBI:16171
Susscrofa domestica IL17A NCBI
Leporidae IL17A NCBI
Rattus norvegicus IL17A NCBI NCBI:301289
Macaca mulatta IL17A NCBI NCBI:708123