IL-17-IN-3
IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. IL-17-IN-3 exhibits no adverse effects in a rat tolerability study after a four-day administration of up to 300 mg/kg/day.
For research use only. We do not sell to patients.
- Formula: C22H25F6N5O3S
- Molecular Weight:553.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 553.52
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Formula C22H25F6N5O3S
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SMILES
O=C(N[C@@H](C1CCC(F)(F)CC1)C(NC2=NC=C(CN3C[C@@H](C(F)(F)F)NC3=O)S2)=O)/C(F)=C\C4CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)