(R)-IL-17 modulator 4
Based on 1 Customer Validation
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4 (HY-141692). IL-17 modulator 4 is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. IL-17 modulator 4 is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.56%
- CAS 番号: 2446804-29-9
- 分子式: C27H34N6O2
- 分子量:474.60
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
IC50 & Target
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IL-17 |
化学情報
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CAS 番号 2446804-29-9
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性状 Solid
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分子量 474.60
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分子式 C27H34N6O2
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Color Off-white to gray
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SMILES
O=C(C1=CC=NN1C(C)C)N[C@@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (210.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1070 mL | 10.5352 mL | 21.0704 mL | 52.6759 mL |
| 5 mM | 0.4214 mL | 2.1070 mL | 4.2141 mL | 10.5352 mL | |
| 10 mM | 0.2107 mL | 1.0535 mL | 2.1070 mL | 5.2676 mL | |
| 15 mM | 0.1405 mL | 0.7023 mL | 1.4047 mL | 3.5117 mL | |
| 20 mM | 0.1054 mL | 0.5268 mL | 1.0535 mL | 2.6338 mL | |
| 25 mM | 0.0843 mL | 0.4214 mL | 0.8428 mL | 2.1070 mL | |
| 30 mM | 0.0702 mL | 0.3512 mL | 0.7023 mL | 1.7559 mL | |
| 40 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3169 mL | |
| 50 mM | 0.0421 mL | 0.2107 mL | 0.4214 mL | 1.0535 mL | |
| 60 mM | 0.0351 mL | 0.1756 mL | 0.3512 mL | 0.8779 mL | |
| 80 mM | 0.0263 mL | 0.1317 mL | 0.2634 mL | 0.6584 mL | |
| 100 mM | 0.0211 mL | 0.1054 mL | 0.2107 mL | 0.5268 mL |