(R)-IL-17 modulator 4
Based on 1 Customer Validation
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4 (HY-141692). IL-17 modulator 4 is a proagent of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. IL-17 modulator 4 is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
For research use only. We do not sell to patients.
- Purity: 99.56%
- CAS No.: 2446804-29-9
- Formula: C27H34N6O2
- Molecular Weight:474.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-17 |
Chemical Information
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CAS No. 2446804-29-9
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Appearance Solid
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Molecular Weight 474.60
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Formula C27H34N6O2
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Color Off-white to gray
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SMILES
O=C(C1=CC=NN1C(C)C)N[C@@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (210.70 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1070 mL | 10.5352 mL | 21.0704 mL | 52.6759 mL |
| 5 mM | 0.4214 mL | 2.1070 mL | 4.2141 mL | 10.5352 mL | |
| 10 mM | 0.2107 mL | 1.0535 mL | 2.1070 mL | 5.2676 mL | |
| 15 mM | 0.1405 mL | 0.7023 mL | 1.4047 mL | 3.5117 mL | |
| 20 mM | 0.1054 mL | 0.5268 mL | 1.0535 mL | 2.6338 mL | |
| 25 mM | 0.0843 mL | 0.4214 mL | 0.8428 mL | 2.1070 mL | |
| 30 mM | 0.0702 mL | 0.3512 mL | 0.7023 mL | 1.7559 mL | |
| 40 mM | 0.0527 mL | 0.2634 mL | 0.5268 mL | 1.3169 mL | |
| 50 mM | 0.0421 mL | 0.2107 mL | 0.4214 mL | 1.0535 mL | |
| 60 mM | 0.0351 mL | 0.1756 mL | 0.3512 mL | 0.8779 mL | |
| 80 mM | 0.0263 mL | 0.1317 mL | 0.2634 mL | 0.6584 mL | |
| 100 mM | 0.0211 mL | 0.1054 mL | 0.2107 mL | 0.5268 mL |
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