6 Results for "

284352

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "284352" in MCE Product Catalog:

23
23 Cited Publications
Cat. No.: HY-50295
CAS No.: 212631-79-3
Synonyms: PD 184352
Target:  

MEK Apoptosis

Research Areas:  

Cancer

CI-1040 (PD 184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1.
Cat. No.: HY-108584
CAS No.: 187523-35-9
Purity:  99.56%
Synonyms: BMS-204352
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo .
Cat. No.: HY-50295A
Synonyms: PD 184352 hydrochloride
Target:  

MEK Apoptosis

Research Areas:  

Cancer

CI-1040 (PD 184352) hydrochloride is an orally active, highly specific inhibitor of MEK, with an IC50 of 17 nM for MEK1 .
Cat. No.: HY-50295R
CAS No.: 212631-79-3
Synonyms: PD 184352 (Standard)
Research Areas:  

Cancer

CI-1040 (Standard) is the analytical standard of CI-1040. This product is intended for research and analytical applications. CI-1040 (PD 184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1.
Cat. No.: HY-108584R
CAS No.: 187523-35-9
Synonyms: BMS-204352 (Standard)
Flindokalner (Standard) is the analytical standard of Flindokalner. This product is intended for research and analytical applications. Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo .
Cat. No.: HY-165191
CAS No.: 124495-31-4
Target:  

Fungal

Research Areas:  

Infection

LY214352 is an antifungal agent that targets dihydroorotate dehydrogenase (DHO-DH). LY214352 exhibits antifungal activity against Aspergillus nidulans and agriculturally important ascomycete fungi. LY214352 can be used in studies related to grape gray mold, apple scab, and fungal infections caused by ascomycetes .