RPUSD3 - RNA pseudouridine synthase D3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 285367

Summary

This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]
Ubiquitous expression in testis (RPKM 19.6), placenta (RPKM 7.8) and 25 other tissues.

RPUSD3 Products (1)

mRNA Protein Name
NG_054931.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of mitochondrial translation IMP
IMP: Inferred from mutant phenotype
27667664 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
28082677 GOA
located in ribonucleoprotein granule IDA
IDA: Inferred from direct assay
28082677 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPUSD3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RPUSD3 Q6P087 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
RPUSD3 Q6P087 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
RPUSD3 Q6P087 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
RPUSD3 Q6P087 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
RPUSD3 Q6P087 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
RPUSD3 Q6P087 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
RPUSD3 Q6P087 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
RPUSD3 Q6P087 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
RPUSD3 Q6P087 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction