BKGD - beta-keto-L-gulonate decarboxylase Gene

Also Known as MEEP; PTD012; PTOD012; C11orf54

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 28970

Summary

Enables hydrolase activity, acting on ester bonds and zinc ion binding activity. Involved in DNA damage response and regulation of DNA repair. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in kidney (RPKM 50.9), liver (RPKM 12.2) and 19 other tissues.

BKGD Products (16)

mRNA Protein Name
NM_001286067.2 NP_001272996.1 beta-keto L-gulonate decarboxylase isoform a
NM_001286068.2 NP_001272997.1 beta-keto L-gulonate decarboxylase isoform a
NM_001286069.2 NP_001272998.1 beta-keto L-gulonate decarboxylase isoform a
NM_001286070.2 NP_001272999.1 beta-keto L-gulonate decarboxylase isoform c
NM_001286071.2 NP_001273000.1 beta-keto L-gulonate decarboxylase isoform d
NM_001351985.2 NP_001338914.1 beta-keto L-gulonate decarboxylase isoform a
NM_001351986.2 NP_001338915.1 beta-keto L-gulonate decarboxylase isoform a
NM_001351987.2 NP_001338916.1 beta-keto L-gulonate decarboxylase isoform a
NM_001351988.2 NP_001338917.1 beta-keto L-gulonate decarboxylase isoform a
NM_001351989.2 NP_001338918.1 beta-keto L-gulonate decarboxylase isoform a
NM_001351990.2 NP_001338919.1 beta-keto L-gulonate decarboxylase isoform c
NM_001351991.2 NP_001338920.1 beta-keto L-gulonate decarboxylase isoform b
NM_001351992.2 NP_001338921.1 beta-keto L-gulonate decarboxylase isoform d
NM_001351993.2 NP_001338922.1 beta-keto L-gulonate decarboxylase isoform e
NM_001369406.2 NP_001356335.1 beta-keto L-gulonate decarboxylase isoform f
NM_014039.4 NP_054758.2 beta-keto L-gulonate decarboxylase isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables hydrolase activity, acting on ester bonds IDA
IDA: Inferred from direct assay
16522806 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
16522806 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BKGD Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
C11orf54 Q9H0W9 VAC14 Homo sapiens Q08AM6
Y2H Array
29892012
Intra
C11orf54 Q9H0W9 VAC14 Homo sapiens Q08AM6
Validated Y2H
25416956
Intra
C11orf54 Q9H0W9 SSX2IP Homo sapiens Q9Y2D8
Y2H Prey Pooling
25416956
Intra
C11orf54 Q9H0W9 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction