2. Gene
  3. Parp2 - poly (ADP-ribose) polymerase 2 Gene

Parp2 - poly (ADP-ribose) polymerase 2 Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Adprtl2

Gene ID: 290027 | Gene type: protein coding

About Parp2

Primary_assembly 15: 24,034,106-24,044,338 forward strand.mRatBN7.2:CM026988.1

This gene has 2 transcripts (splice variants), 185 orthologues, 2 paralogues and is associated with 2 phenotypes.

Summary

Predicted to enable nucleosome binding activity and pentosyltransferase activity. Involved in negative regulation of neuron death and positive regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in nucleoplasm and site of DNA damage. Predicted to be active in nucleolus. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2). [provided by Alliance of Genome Resources, Apr 2022]

Parp2 Products(1)

mRNA Protein Name
NM_001106030.1 NP_001099500.1 poly [ADP-ribose] polymerase 2

Related Agents

Approval
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10162 Olaparib Inhibitor 99.98% Yes
HY-16106 Talazoparib Inhibitor 99.89% Unkown
HY-10619 Niraparib Inhibitor 99.96% Yes
HY-10617A Rucaparib Inhibitor 99.80% Yes
HY-10619B Niraparib tosylate Inhibitor 99.99% Yes
HY-10619A Niraparib hydrochloride Inhibitor 99.76% Yes
HY-10617 Rucaparib phosphate Inhibitor 99.76% Yes
HY-102003 Rucaparib monocamsylate Inhibitor 99.82% Yes
HY-10619E Niraparib tosylate hydrate Inhibitor 99.97% Yes
HY-102003A Rucaparib camsylate Inhibitor / Unkown
HY-10617C Rucaparib tartrate Inhibitor / Unkown
HY-10617D Rucaparib acetate Inhibitor / Unkown
HY-10617B Rucaparib hydrochloride Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-10129 Veliparib Inhibitor 99.92% Phase 3
HY-10130 Veliparib dihydrochloride Inhibitor 99.96% Phase 3
HY-132167 Saruparib Inhibitor 99.79% Phase 2
HY-12418 Stenoparib Inhibitor ≥98.0% Phase 2
HY-105303 CEP-9722 Inhibitor / Phase 2
HY-13536 AZD-2461 Inhibitor 99.88% Phase 1
HY-115552 Simmiparib Inhibitor 99.51% Phase 1
Pre-clinical Phase
Bioactive Molecules (33)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15147 XAV-939 Inhibitor 99.91% Unkown
HY-13688A PJ34 Inhibitor 98.11% Unkown
HY-13688 PJ34 hydrochloride Inhibitor 99.91% Unkown
HY-13990 NVP-TNKS656 Inhibitor 99.66% Unkown
HY-150207 RBN-3143 Inhibitor 99.24% Unkown
HY-137457 Venadaparib Inhibitor 98.11% Unkown
HY-12975 AZ6102 Inhibitor 99.65% Unkown
HY-18954 NMS-P118 Inhibitor 99.78% Unkown
HY-14478 UPF 1069 Inhibitor 99.10% Unkown
HY-19351 MN-64 Inhibitor 99.73% Unkown
HY-122661 Mefuparib hydrochloride Inhibitor 98.94% Unkown
HY-10614 A-966492 Inhibitor 99.95% Unkown
HY-108632 BYK204165 Inhibitor 98.66% Unkown
HY-132297A PARP1-IN-5 dihydrochloride Inhibitor 97.21% Unkown
HY-148566 OUL232 Inhibitor 99.82% Unkown
HY-143338 ART-IN-1 Inhibitor 98.91% Unkown
HY-121719 TIQ-A Inhibitor 99.65% Unkown
HY-156419 PARP7-IN-16 Inhibitor / Unkown
HY-147886 PARP1-IN-11 Inhibitor 98.58% Unkown
HY-133124 PARP/PI3K-IN-1 Inhibitor 99.43% Unkown
HY-148754 PARP10-IN-3 Inhibitor 98.89% Unkown
HY-105692 DR2313 Inhibitor 98.70% Unkown
HY-132297 PARP1-IN-5 Inhibitor / Unkown
HY-102035 PARP-2-IN-1 Inhibitor / Unkown
HY-137457A Venadaparib hydrochloride Inhibitor / Unkown
HY-151625 PARP-2-IN-3 Inhibitor / Unkown
HY-105253 PARP-2/1-IN-2 Inhibitor / Unkown
HY-145749 PARPYnD Inhibitor / Unkown
HY-146336 PARP1/2/TNKS1/2-IN-1 Inhibitor / Unkown
HY-W294889 OUL245 Inhibitor / Unkown
HY-148753 PARP10-IN-2 Inhibitor 98.02% Unkown
HY-155993 YCH1899 Inhibitor / Unkown
HY-149800 PARP-1-IN-3 Inhibitor 99.30% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Parp2 NCBI NCBI:10038