1. Neuronal Signaling Immunology/Inflammation Epigenetics Cell Cycle/DNA Damage MAPK/ERK Pathway Apoptosis Metabolic Enzyme/Protease
  2. Cholinesterase (ChE) Monoamine Oxidase NO Synthase PARP p38 MAPK RIP kinase Phospholipase Indoleamine 2,3-Dioxygenase (IDO) Dihydroorotate Dehydrogenase
  3. NDs-IN-1

(Neurodegenerative diseases) NDs-IN-1 (Compound 3g) inhibits the activities of key enzymes such as hBACE-1, hAChE and hMAO-B. NDs-IN-1 is a novel non-covalent multi-target inhibitor. NDs-IN-1 is mainly used in the study of neurodegenerative diseases.

For research use only. We do not sell to patients.

NDs-IN-1 Chemical Structure

NDs-IN-1 Chemical Structure

CAS No. : 3033806-97-9

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Description

(Neurodegenerative diseases) NDs-IN-1 (Compound 3g) inhibits the activities of key enzymes such as hBACE-1, hAChE and hMAO-B. NDs-IN-1 is a novel non-covalent multi-target inhibitor. NDs-IN-1 is mainly used in the study of neurodegenerative diseases[1].

IC50 & Target

p38 MAPK

 

hMAO-A

 

hMAO-B

 

hAChE

 

hBCHE

 

nNOS

 

iNOS

 

hPARP-1

 

PARP-2

 

IDO-1

 

RIPK1

 

Molecular Weight

318.37

Formula

C20H18N2O2

CAS No.
Unlabeled CAS

SMILES

COC1=CC=C(C2=NN=C3C4=CC=CC=C4CCC3=C2)C=C1OC

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NDs-IN-1
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