PARP1-IN-35
PARP1-IN-35 (compound T26) is a selective, orally active, cross -the blood-brain barrierPARP1 inhibitor with IC50 values of 0.2, 122 nM for PARP1, PARP2, respectively. PARP1-IN-35 shows antiproliferative activity and anticancer activity. PARP1-IN-35 has the potential for the research of breast cancer.
For research use only. We do not sell to patients.
- Formula: C22H21N5O
- Molecular Weight:371.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PARP1 0.2 nM (IC50) |
PARP2 122 nM (IC50) |
Chemical Information
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Molecular Weight 371.44
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Formula C22H21N5O
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SMILES
O=C1NC2=C(C=C1CC)N=CC(CN3CC=C(CC3)C4=CC=C(C=N4)C#N)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)