Venadaparib hydrochloride
Based on 1 publication(s) in Google Scholar
Venadaparib (IDX-1197) hydrochloride is a potent and selective PARP inhibitor with anticancer activities. Venadaparib hydrochloride can be used for solid tumors research.
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- No. CAS: 1681020-60-9
- Fòrmula: C23H24ClFN4O2
- Peso molecular:442.91
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Venadaparib hydrochloride
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
PARP1 1.4 nM (IC50) |
PARP2 1 nM (IC50) |
In Vitro
Venadaparib (example 143; 6-10 days) shows potent growth inhibition of MDA-MB-436 cells and Capan-1 pancreatic cancer cells with IC50 values of ≤5nM and 50nM
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1681020-60-9
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Peso molecular 442.91
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Fòrmula C23H24ClFN4O2
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SMILES
O=C1NN=C(CC2=CC=C(F)C(C(N3CC(CNC4CC4)C3)=O)=C2)C5=C1C=CC=C5.[H]Cl
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Synonyms
IDX-1197 hydrochloride
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)