SSU72 - SSU72 homolog, RNA polymerase II CTD phosphatase Gene

Homo sapiens

Also known as HSPC182; PNAS-120

Gene ID: 29101 | Gene type: protein coding

About SSU72

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,541,673-1,574,863 (from NCBI)

This gene has 4 transcripts (splice variants), 157 orthologues and 6 paralogues. Ubiquitous expression in thyroid (RPKM 50.5), fat (RPKM 49.2) and 25 other tissues.

Summary

Enables RNA polymerase II CTD heptapeptide repeat Phosphatase activity. Involved in dephosphorylation of RNA polymerase II C-terminal domain and mRNA polyadenylation. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SSU72 Products(1)

mRNA	Protein	Name
NM_014188.3	NP_054907.1	RNA polymerase II subunit A C-terminal domain phosphatase SSU72

SSU72 Protein Structure

Ssu72

0
100
194 a.a.

Protein Preferred Names

Protein Names

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

CTD phosphatase SSU72

Related Diseases

Diseases

Alias

Albinism, Oculocutaneous, Type V

OCA5	Oculocutaneous Albinism Type V
Oculocutaneous Albinism Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13835	SSU72 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SSU72	VGNC	VGNC:77986
Rattus norvegicus	SSU72	RGD	RGD:1307854
Mus musculus	SSU72	MGD	MGI:1916241

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