Bpi - bactericidal/permeability-increasing protein Gene

Also Known as Bpifd1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296321

Summary

Enables lipopolysaccharide binding activity. Involved in defense response to bacterium and immune response. Located in cytoplasm. Human ortholog(s) of this gene implicated in Crohn's disease. Orthologous to human BPI (bactericidal permeability increasing protein). [provided by Alliance of Genome Resources, Apr 2022]

Bpi Products (1)

mRNA Protein Name
NM_001004079.1 NP_001004079.1 bactericidal permeability-increasing protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
15009116 RGD
Biological Process GO Annotation Evidence References Source
involved in defense response to bacterium IDA
IDA: Inferred from direct assay
11445707 RGD
involved in immune response IDA
IDA: Inferred from direct assay
11445707 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bactericidal permeability-increasing protein

  • BPI fold containing family D, member 1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15164A Icotinib Inhibitor 99.96% Yes
HY-15164 Icotinib Hydrochloride Inhibitor 99.89% Yes

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-109189A Rezivertinib hydrochloride Inhibitor / Phase 3
HY-114356 BPI-9016M Inhibitor 97.13% Phase 1
HY-164464 BPI-15086 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-109189 Rezivertinib Inhibitor 99.62% Unkown
HY-141703A DC-BPi-11 hydrochloride Inhibitor 97.36% Unkown
HY-150211 DC-BPi-03 Inhibitor 99.77% Unkown
HY-156646 Tibremciclib Inhibitor / Unkown
HY-141703 DC-BPi-11 Inhibitor / Unkown
HY-15164AS Icotinib-d4 / Unkown
HY-173165 OA-Br-1 / Unkown
HY-178697 DC-BPi-07 Inhibitor / Unkown
HY-RS01580 BPI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18324 Bpi Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24802 Bpi Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bpi NCBI NCBI:671